ID Design 2012/DOOEL Skopje, Republic of
Open Access Macedonian Journal of Medical Sciences.
Indicators of Asthma Control in Asthmatic Patients: Are they related to
Tarig H. Merghani*, Azza O. Alawad
Department of Physiology, Faculty of Medicine,
University of Tabuk, Tabuk, Saudi Arabia
Many patients with chronic illnesses suffer from depression. A poorly
controlled asthma that presents with repeated attacks of breathlessness is a
recognised risk factor for bipolar disorders. On the other hand, depression
can aggravate asthma symptoms.
The aim of this study is to determine the indicators of the asthma control
test (ACT) among the asthmatic patients who attend the outpatient clinic for
follow-up and to investigate the relation between these indicators and
clinical depression, using a standardised depression scale.
A total of 38 adult asthmatic patients (29 women, age 17–85 years), with
variable levels of control, were assessed using the ACT and the Beck
Depression Inventory (BDI). Data obtained were analysed with the Statistical
Package for the Social Sciences (SPSS Inc., Chicago, IL, USA) version 20.
The association of depression with the various indicators of asthma control
was analysed with the Chi-Square test. Statistical significance was
determined at p< 0.05.
The uncontrolled asthma is associated with depression in 37% of all
participants compared to 0% in the well-controlled group (p = 0.002).
Depression is significantly related to asthma interference with daily
activities (p = 0.003), breathlessness (p < 0.001), night symptoms (p =
0.036), use of bronchodilators (p = 0.007), and poor compliance with medical
treatment (p = 0.003). The poor educational attainment and comorbidities
have significant relations to both uncontrolled asthma and clinical
depression (p < 0.05).
All indicators of the poor asthma control are associated with clinical
depression. A significant proportion of the uncontrolled asthma patients
suffers from depression. The possibility of improving asthma control with a
pharmacological treatment of depression has to be considered.
Citation: Merghani TH, Alawad AO. Indicators of
Asthma Control in Asthmatic Patients: Are they related to Depression? Open
Access Maced J Med Sci. https://doi.org/10.3889/oamjms.2017.091
Keywords: Asthma; Depression; Asthma Control.
*Correspondence: Tarig H. Merghani. Department of Physiology, Faculty
of Medicine, University of Tabuk, Tabuk, Saudi Arabia. E-mail: email@example.com
Received: 07-May-2017; Revised: 05-Jun-2017; Accepted: 06-Jun-2017; Online
Copyright: © 2017 Tarig H. Merghani, Azza O. Alawad. This is an
open-access article distributed under the terms of the Creative Commons
Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
Funding: The Deanship of Scientific Research (DSR), the University of
Tabuk, Tabuk, Saudi Arabia.
Competing Interests: Publication of this paper has been supported by
Roche Macedonia DOOEL Skopje.
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- Merghani TH
- Alawad AO