ID Design 2012/DOOEL Skopje, Republic of
Macedonia
Open Access Macedonian Journal of Medical Sciences.
https://doi.org/10.3889/oamjms.2017.038
eISSN: 1857-9655
Case Report
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Early and Late Complications in
Patients with Allogeneic Transplantation of Hematopoietic Stem Cell – Case
Report
Ivana Trajkovska1*, Borce Georgievski2,
Lidija Cevreska2, Andrijana Gacovski3, Taner Hasan1,
Natasha Nedeska-Minova1
1GOB “8-mi Septemvri” Skopje, Skopje, Republic of Macedonia;
2University Clinic of Hematology, Medical Faculty, Ss Cyril and
Methodius University of Skopje, Skopje, Republic of Macedonia; 3Primary
Health Care “D-r Vasileva Cardio”, Skopje, Republic of Macedonia
BACKGROUND: Allogeneic hematopoietic stem cells transplantation (HSCT)
is a curative intervention in patients with haematological malignant and
non-malignant diseases, immunodeficiency, autoimmune, and other genetic
diseases. Early complications are complications that are occurring in the
first 100 days, while complications arising after the 100th day of
transplantation belong to late complications.
CASE REPORT: Forty-nine years old patient with AML treated with
allogeneic HSCT from HLA-identical (sister) donor. Ascertained and display
of early (acute Graft versus host disease (GvHD) and late complications
(chronic GVHD, infections, cataract, secondary malignancy with MS deposits)
are made, that emerged after the patient transplantation.
CONCLUSION: Rapidly growing population of patients that undergo
allogeneic HSCT creates an obligation to educate patients and physicians
about observed late complications that occur after this therapy.
..................
Citation: Trajkovska I, Georgievski B, Cevreska L,
Gacovski A, Hasan T, Nedeska-Minova N. Early and Late Complications in
Patients with Allogeneic Transplantation of Hematopoietic Stem Cell – Case
Report. Open Access Maced J Med Sci. https://doi.org/10.3889/oamjms.2017.038
Keywords: allogeneic hematopoietic stem cells transplantation; early
and late complications; graft versus host disease; secondary malignancy.
*Correspondence: Ivana Trajkovska. GOB “8-mi Septemvri” Skopje,
Skopje, Republic of Macedonia. E-mail: trajkovska.ivana85@gmail.com
Received: 23-Jan-2017; Revised: 24-Mar-2017; Accepted: 21-Apr-2017; Online
first: 09-May-2017
Copyright: © 2017 Ivana Trajkovska, Borce Georgievski, Lidija
Cevreska, Andrijana Gacovski, Taner Hasan, Natasha Nedeska-Minova. This is an open-access article
distributed under the terms of the Creative Commons Attribution-NonCommercial
4.0 International License (CC BY-NC 4.0).
Funding: This research did not receive any financial support.
Competing Interests: The authors have declared that no competing
interests exist.
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Trajkovska I
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Georgievski B
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Cevreska L
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Gacovski A
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Hasan T
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Nedeska-Minova N
PubMed
- Trajkovska I
- Georgievski B
- Cevreska L
- Gacovski A
- Hasan T
- Nedeska-Minova N
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