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ID Design 2012/DOOEL Skopje, Republic of Macedonia

Open Access Macedonian Journal of Medical Sciences.

https://doi.org/10.3889/oamjms.2017.038

eISSN: 1857-9655

Case Report

 

 

 

Early and Late Complications in Patients with Allogeneic Transplantation of Hematopoietic Stem Cell – Case Report


 

Ivana Trajkovska1*, Borce Georgievski2, Lidija Cevreska2, Andrijana Gacovski3, Taner Hasan1, Natasha Nedeska-Minova1


1GOB “8-mi Septemvri” Skopje, Skopje, Republic of Macedonia; 2University Clinic of Hematology, Medical Faculty, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; 3Primary Health Care “D-r Vasileva Cardio”, Skopje, Republic of Macedonia

 

Abstract

 

 

BACKGROUND: Allogeneic hematopoietic stem cells transplantation (HSCT) is a curative intervention in patients with haematological malignant and non-malignant diseases, immunodeficiency, autoimmune, and other genetic diseases. Early complications are complications that are occurring in the first 100 days, while complications arising after the 100th day of transplantation belong to late complications.

CASE REPORT: Forty-nine years old patient with AML treated with allogeneic HSCT from HLA-identical (sister) donor. Ascertained and display of early (acute Graft versus host disease (GvHD) and late complications (chronic GVHD, infections, cataract, secondary malignancy with MS deposits) are made, that emerged after the patient transplantation.

CONCLUSION: Rapidly growing population of patients that undergo allogeneic HSCT creates an obligation to educate patients and physicians about observed late complications that occur after this therapy.

..................

Citation: Trajkovska I, Georgievski B, Cevreska L, Gacovski A, Hasan T, Nedeska-Minova N. Early and Late Complications in Patients with Allogeneic Transplantation of Hematopoietic Stem Cell – Case Report. Open Access Maced J Med Sci. https://doi.org/10.3889/oamjms.2017.038
Keywords: allogeneic hematopoietic stem cells transplantation; early and late complications; graft versus host disease; secondary malignancy.
*Correspondence: Ivana Trajkovska. GOB “8-mi Septemvri” Skopje, Skopje, Republic of Macedonia. E-mail: trajkovska.ivana85@gmail.com
Received: 23-Jan-2017; Revised: 24-Mar-2017; Accepted: 21-Apr-2017; Online first: 09-May-2017
Copyright: © 2017 Ivana Trajkovska, Borce Georgievski, Lidija Cevreska, Andrijana Gacovski, Taner Hasan, Natasha Nedeska-Minova. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
Funding: This research did not receive any financial support.
Competing Interests: The authors have declared that no competing interests exist.
 

 

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- Trajkovska I
- Georgievski B
- Cevreska L
- Gacovski A
- Hasan T
- Nedeska-Minova N


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- Trajkovska I
- Georgievski B
- Cevreska L
- Gacovski A
- Hasan T
- Nedeska-Minova N

 

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Published by: Id Design 2012/DOOEL Skopje, Republic of Macedonia


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.