Can Low Level Laser Therapy Benefit Bone Regeneration in Localized Maxillary Cystic Defects? - A Prospective Randomized Control Trial

¹National Institute of Laser Enhanced Sciences, Cairo University, Cairo, Egypt; ²Surgery and Oral Medicine Department, National Research Center, Cairo, Egypt; ³Oral Surgery and Medicine Department, National Research Center, Cairo, Egypt

AIM: The aim of the study was to evaluate the effect of Low-Level Laser Therapy (LLLT) on bone formation in cystic defects following cyst enucleation.

PATIENTS AND METHODS: The sample was composed of sixteen patients with enucleated maxillary bony cystic lesions. With an age range from 20 - 44 grouped as eight Laser and eight Control patients. Laser group was subjected to low intensity diode laser immediately after surgery and then for three times per week for two weeks using a therapeutic laser irradiation. Group B (control group): patients were not subjected laser therapy.

RESULTS: The predictor variable was exposure of bone defect to LLLT or none. The outcome variable was bone density changes measured by digital radiographs at day 1 and days 90 postoperatively. Descriptive and bivariate statistics were computed. There were no statistically significant differences between the 2 groups for the bone density at day 1. There was a statistically significant difference in bone density changes in each group at day 90: Significant at P ≤ 0.05. After adjusting for differences in day 1 for bone density, the estimated mean change in bone density changes at day 90 was significantly larger for Laser compared with control.

Citation: Zaky AA, El Shenawy HMM, Harhsh TAH, Shalash M, Awad NMI. Can Low Level Laser Therapy Benefit Bone Regeneration in Localized Maxillary Cystic Defects? - A Prospective Randomized Control Trial. Open Access Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2016.140
Keywords: LLLT; low intensity pulsed ultrasound; cystic lesion; digital radiograph.
*Correspondence: Associate Prof. Dr Hanaa Mohamed Elshenawy. Surgery and Oral Medicine Department, National Research Center, Cairo, Egypt. E-mail: dr.hanaa.shenawy@gmail.com
Received: 20-Nov-2016; Revised: 24-Nov-2016; Accepted: 26-Nov-2016; Online first: 13-Dec-2016
Copyright: © 2016 Ahmed Abbas Zaky, Hanaa Mohamed Mohamed El Shenawy, Tarek Abdel Hamed Harhsh, Mahmoud Shalash, Noha Mohamed Ismael Awad. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
Funding: This research did not receive any financial support.
Competing Interests: The authors have declared that no competing interests exist.

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