ID Design 2012/DOOEL Skopje, Republic of
Macedonia
Open Access Macedonian Journal of Medical Sciences.
http://dx.doi.org/10.3889/oamjms.2016.091
eISSN: 1857-9655
Clinical Science
|
|
Clinical, Laboratory and
Radiographic Features of Patients with Pneumonia and Parapneumonic Effusions
Sanja Petrusevska-Marinkovic1*, Irena
Kondova-Topuzovska1, Zvonko Milenkovic1, Goran Kondov2,
Ankica Anastasovska1
1University Infectious Diseases Clinic, Medical Faculty, Ss Cyril
and Methodius University of Skopje, Skopje, Republic of Macedonia; 2University
Thoracocardiovascular Surgery Clinic, Medical Faculty, Ss Cyril and
Methodius University of Skopje, Skopje, Republic of Macedonia
BACKGROUND: Parapneumonic effusions complicating pneumonia are
associated with increased morbidity and mortality.
AIM: To determine the role of the clinical, laboratory and
radiographic features to the differential diagnosis of patients with
community- acquired pneumonia (CAP) without effusion, uncomplicated
parapneumonic effusion (UCPPE) and complicated parapneumonic effusion (CPPE).
MATERIAL AND METHODS: We analysed 148 patients with CAP without
effusion, 50 with UCPPE and 44 with CPPE. In three groups of patients, the
majority was male patients (58.11%, 58%, 61.36%) consequently.
RESULTS: The chronic heart failure was the most common comorbidity in
a group with CAP (28; 18.92%) and UCPPE (7; 14%), alcoholism (12;12.77%) in
a group with CPPE. Patients with CPPE had significantly longer fever
compared to patients with CAP without effusion (p = 0.003). Pleuritic chest
pain (86.36%) and dyspnea (88.64%) were the most common symptoms in CPPE,
then to group with UCPPE (60%; 52%), and in CAP without effusion (25.68%;
47,97%). Diffuse pulmonary changes were detected more frequently in the
group with CAP without effusion compared with the group with CPPE (64.86 %
vs. 27.27 %), while the segment lung changes were more common in patients
with CPPE (50% vs. 20.27%). Patients with CPPE were significant with higher
erythrocytes sedimentation rate (ESR), white blood cells (WBC) and serum C-
reactive protein (CRP) than it the other two groups (p = 0.00090, p = 0.01,
p= 0.000065).
CONCLUSION: Proper analysis of clinical, laboratory and radiographic
features of patients with CAP and parapneumonic effusion can prevent
mismanagement in these patients and will reduce morbidity and mortality.
..................
Citation: Petrusevska-Marinkovic S,
Kondova-Topuzovska I, Milenkovic Z, Kondov G, Anastasovska A. Clinical,
Laboratory and Radiographic Features of Patients with Pneumonia and
Parapneumonic Effusions. Open Access Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2016.091
Keywords: community-acquired pneumonia (CAP); parapneumonic effusion;
empyema; clinical features; laboratory features; radiographic features.
*Correspondence: Sanja Petrusevska Marinkovic, MD. University
Infectious Diseases Clinic, Medical Faculty, Ss Cyril and Methodius
University of Skopje, Skopje, Republic of Macedonia. Tel.: 00389 72 206 661.
E-mail: sanjapm@yahoo.com
Received: 22-Jul-2016; Revised: 08-Aug-2016; Accepted: 22-Aug-2016; Online
first: 23-Aug-2016
Copyright: © 2016 Sanja Petrusevska-Marinkovic, Irena
Kondova-Topuzovska, Zvonko Milenkovic, Goran Kondov, Ankica Anastasovska.
This is an open access article distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use, distribution,
and reproduction in any medium, provided the original author and source are
credited.
Competing Interests: The authors have declared that no competing
interests exist.
|
<
Previous
|
Next Article >
Table of contents
This Article
(free)
Full text (pdf)
Full text OnlineFirst (pdf)
Google Scholar
-
Petrusevska-Marinkovic S
-
Kondova-Topuzovska I
-
Milenkovic Z
-
Kondov G
-
Anastasovska A
PubMed
- Petrusevska-Marinkovic S
- Kondova-Topuzovska I
- Milenkovic Z
- Kondov G
- Anastasovska A
|