Beti Zafirova-Ivanovska¹, Jagoda Stojkovikj^2*, Dejan Dokikj², Sasha Anastasova³, Angela Debresliovska², Sead Zejnel², Dragana Stojkovikj<sup>4

1</sup>Institute for Epidemiology and Biostatistics and Medical Informatics, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; ²University Clinic of Pulmonology and Allergology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; ³University Clinic of Cardiology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; ⁴School of Doctoral Studies at Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia

AIM: The aim of the study was to investigate the prevalence of diabetes mellitus in privies diagnosed chronic obstructive pulmonary disease (COPD) patients with severe and very severe disease, which ware stable.

METHODS: We investigated 100 subjects, all of them smokers, with smoking status >10 years. They were stratified in two groups. It was clinical, randomized, cross sectional study. Besides demographic parameters, functional parameters, BMI, cholesterol, LDL and HDL, and the level of blood sugar was measured.

RESULTS: The prevalence of diabetes mellitus in our survey in total number of COPD patients with severe and very severe stage was 21%. In the very severe group were recorded significantly higher average values of glycaemia compared with severe group (7.67 ± 3.7 vs. 5.62 ± 0.9, p = 0.018). In the group with severe COPD, it was not confirmed any factor with significant predictive effect on the values of glycaemia. As independent significant factors that affect blood glucose in a group of very severe COPD were confirmed cholesterol (p <0.0001) and HDL (p = 0.018).

CONCLUSION: These results suggest that the presence of the COPD in patients itself is a factor that results in the clinical presentation of diabetes mellitus Type 2.
 

Citation: Zafirova-Ivanovska B, Stojkovikj J, Dokikj D, Anastasova S, Debresliovska A, Zejnel S, Stojkovikj D. The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2016.063
Keywords: severe and very severe COPD; comorbidity; the level of cholesterol; the level of LDL; the level of HDL.
*Correspondence: Dr. Jagoda Stojkovikj. University Clinic of Pulmonology and Allergology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, ul. Majka Tereza n. 17, Skopje 1000, Republic of Macedonia. E-Mail: stojkovic_jagoda@yahoo.com
Received: 13-Apr-2016; Revised: 12-May-2016; Accepted: 14-May-2016; Online first: 24-May-2016
Copyright: © 2016 Beti Zafirova-Ivanovska, Jagoda Stojkovikj, Dejan Dokikj, Sasha Anastasova, Angela Debresliovska, Sead Zejnel, Dragana Stojkovikj.   This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Competing Interests: The authors have declared that no competing interests exist.
 

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