Jagoda Stojkovikj^1*, Beti Zafirova-Ivanovska², Biserka Kaeva¹, Sasha Anastasova³, Irena Angelovska¹, Smiljko Jovanovski¹, Dragana Stojkovikj<sup>4

1</sup>University Clinic of Pulmollogy and Allergology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; ²Institute for Epidemiology and Biostatistics and Medical Informatics, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; ³University Clinic of Cardiology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; ⁴School of Doctoral Studies at Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia

AIM: The aim of the study was to investigate the prevalence of diabetes mellitus in privies diagnosed chronic obstructive pulmonary disease (COPD) patients with severe and very severe disease, which ware stable.

METHODS: We investigated 100 subjects, all of them smokers, with smoking status >10 years. They were stratified in two groups. It was clinical, randomized, cross sectional study. Besides demographic parameters, functional parameters, BMI, cholesterol, LDL and HDL, and the level of blood sugar was measured.

RESULTS: The prevalence of diabetes mellitus in our survey in total number of COPD patients with severe and very severe stage was 21%. In the very severe group were recorded significantly higher average values of glycaemia compared with severe group (7.67 ± 3.7 vs. 5.62 ± 0.9, p = 0.018). In the group with severe COPD, it was not confirmed any factor with significant predictive effect on the values of glycaemia. As independent significant factors that affect blood glucose in a group of very severe COPD were confirmed cholesterol (p <0.0001) and HDL (p = 0.018).

CONCLUSION: These results suggest that the presence of the COPD in patients itself is a factor that results in the clinical presentation of diabetes mellitus Type 2.
 

Citation: Stojkovikj J, Zafirova-Ivanovska B, Kaeva B, Anastasova S, Angelovska I, Jovanovski S, Stojkovikj D. The Prevalence of Diabetes Mellitus in COPD Patients with Severe and Very Severe Stage of the Disease. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2016.060
Key words: severe COPD; very severe COPD; comorbidity; prevalence of diabetes mellitus type 2.
*Correspondence: Dr. Jagoda Stojkovikj. University Clinic of Pulmollogy and Allergology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, ul. Majka Tereza n. 17, Skopje 1000, Republic of Macedonia. E-Mail: stojkovic_jagoda@yahoo.com
Received: 13-Apr-2016; Revised: 10-May-2016; Accepted: 11-May-2016; Online first: 22-May-2016
Copyright: © 2016 Jagoda Stojkovikj, Beti Zafirova-Ivanovska, Biserka Kaeva, Sasha Anastasova, Irena Angelovska, Smiljko Jovanovski, Dragana Stojkovikj.  This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Competing Interests: The authors have declared that no competing interests exist.
 

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