ID Design 2012/DOOEL Skopje
Open Access Macedonian Journal of Medical Sciences.
http://dx.doi.org/10.3889/oamjms.2016.053
eISSN: 1857-9655
Clinical Science
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Anticoagulation Management in
Patients with Pacemaker-Detected Atrial Fibrillation
Lidija Poposka*, Vladimir Boskov, Dejan
Risteski, Jane Taleski, Ljubica Georgievska-Ismail
University Clinic of Cardiology, Faculty of Medicine, Ss Cyril and Methodius
University of Skopje, Skopje, Republic of Macedonia
INTRODUCTION: In patients with an implanted pacemaker, asymptomatic
atrial fibrillation (AF) is associated with an increased risk of thrombo-embolic
complications. There is still no consensus which duration of episodes of
atrial fibrillation should be taken as an indicator for inclusion of oral
anticoagulation therapy (OAC).
MATERIAL AND METHODS: A total of 104 patients who had no AF episodes
in the past and have an indication for permanent pacing were included in the
study.
RESULTS: During an average follow-up of 18 months, 33 of the patients
developed episodes of AF. Inclusion of OAC was performed in 17 patients, in
whom AF was recorded, although in all patients CHA2DS2-VASc score was ≥ 1.
The inclusion of OAC showed a statistically significant correlation with
increasing duration of episodes of AF (r = 0.502, p = 0.003). During the
follow-up period none of the patients developed thrombo-embolic
complication.
CONCLUSION: Considering that our group of patients had no thrombo-embolic
events, we could conclude that dividing the AF episodes in less than 1% in
24 hours and longer than 1% within 24 hours could be an indicator for
decision-making to include OAK if the CHA2DS2-VASc score is ≥ 1.
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Citation: Poposka L, Boskov V, Risteski D, Taleski
J, Georgievska-Ismail Lj. Anticoagulation Management in Patients with
Pacemaker-Detected Atrial Fibrillation. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2016.053
Key words: atrial fibrillation; pacemaker; anticoagulants; thrombo-embolic
events; asymptomatic.
*Correspondence: Dr. Lidija Poposka. University Clinic of Cardiology,
Vodnjanska 17, Skopje 1000, Macedonia. Phone: +389 2 3147 533. E-Mail:
lidijapoposka@gmail.com
Received: 10-Mar-2016; Revised: 15-Apr-2016; Accepted: 16-Apr-2016; Online
first: 20-Apr-2016
Copyright: © 2016 Lidija Poposka, Vladimir Boskov, Dejan Risteski,
Jane Taleski, Ljubica Georgievska-Ismail.
This is an open access article distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use, distribution,
and reproduction in any medium, provided the original author and source are
credited.
Competing Interests: The authors have declared that no competing
interests exist.
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Poposka L
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Boskov V
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Risteski D
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Taleski
J
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Georgievska-Ismail Lj
PubMed
- Poposka L
- Boskov V
- Risteski D
- Taleski J
- Georgievska-Ismail Lj
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