ID Design 2012/DOOEL Skopje
Open Access Macedonian Journal of Medical Sciences.
http://dx.doi.org/10.3889/oamjms.2016.046
eISSN: 1857-9655
Public Health
|
|
Hormonal Perturbations in
Occupationally Exposed Nickel Workers
Safia Beshir*, Khadiga Salah Ibrahim, Weam Shaheen, Eman
M. Shahy
Environmental and Occupational Medicine Department, National Research
Centre, Dokki, Giza, Egypt
BACKGROUND: Nickel exposure is recognized as an endocrine disruptor
because of its adverse effects on reproduction.
AIM: This study was designed to investigate the possible testiculo-hormonal
perturbations on workers occupationally exposed to nickel and to assess its
effects on human male sexual function.
METHODS: Cross-sectional comparative study, comprising 105
electroplating male non-smoker, non-alcoholic workers exposed to soluble
nickel and 60 controls was done. Serum luteinizing hormone, follicle
stimulating hormone, testosterone levels and urinary nickel concentrations
were determined for the studied groups.
RESULTS: Serum luteinizing hormone, follicle stimulating hormone,
urinary nickel and the simultaneous incidence of more than one sexual
disorder were significantly higher in the exposed workers compared to
controls. The occurrence of various types of sexual disorders (decreased
libido, impotence and premature ejaculation) in the exposed workers was 9.5,
5.1 and 4.4 folds respectively than the controls.
CONCLUSIONS: Exposure to nickel produces possible testiculo-hormonal
perturbations in those exposed workers.
..................
Citation: Beshir S, Ibrahim KS, Shaheen W, Shahy
EM. Hormonal Perturbations in Occupationally Exposed Nickel Workers. OA
Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2016.046
Key words: Nickel; FSH; LH; Testosterone; sexual problems.
*Correspondence: Safia Beshir Ahmed. Professor of Environmental
Health, Environmental and Occupational Medicine Department. National
Research Centre , 33 EL Bohouth st. (former EL Tahrir st.) - Dokki – Giza –
Egypt – P.O. 12622. Tel.: 002 01006285633. E-mail: safiabeshir123@yahoo.com
Received: 07-Feb-2016; Revised: 13-Mar-2016; Accepted: 14-Mar-2016; Online
first: 31-Mar-2016
Copyright: © 2016 Safia Beshir, Khadiga Salah Ibrahim, Weam Shaheen,
Eman M. Shahy.
This is an open access article distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use, distribution,
and reproduction in any medium, provided the original author and source are
credited.
Competing Interests: The authors have declared that no competing
interests exist.
|
<
Previous
|
Next Article >
Table of contents
This Article
(free)
Full text (pdf)
Full text OnlineFirst (pdf)
Google Scholar
-
Beshir S
-
Ibrahim KS
-
Shaheen W
-
Shahy EM
PubMed
- Beshir S
- Ibrahim KS
- Shaheen W
- Shahy EM
|