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ID Design 2012/DOOEL Skopje

Open Access Macedonian Journal of Medical Sciences.

http://dx.doi.org/10.3889/oamjms.2016.030
eISSN: 1857-9655

Clinical Science

 

 

Report on von Willebrand Disease in Malaysia


 

Mercy Halleluyah Periayah1, Ahmad Sukari Halim1*, Arman Zaharil Mat Saad1, Nik Soriani Yaacob2, Faraizah Abdul Karim3

1Reconstructive Sciences Unit, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia; 2Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia; 3Hemophilia Clinic, National Blood Centre (Pusat Darah Negara), Jalan Tun Razak, 50400, Wilayah Persekutuan, Kuala Lumpur

 

Abstract

 

 

BACKGROUND: Von Willebrand disease (vWD) is an inherited hemostatic disorder that affects the hemostasis pathway. The worldwide prevalence of vWD is estimated to be 1% of the general population but only 0.002% in Malaysia.

AIM: Our present paper has been written to disclose the statistical counts on the number of vWD cases reported from 2011 to 2013.

MATERIAL AND METHODS: This article is based on sociodemographic data, diagnoses and laboratory findings of vWD in Malaysia. A total of 92 patients were reported to have vWD in Malaysia from 2011 to 2013.

RESULTS: Sociodemographic-analysis revealed that 60% were females, 63% were of the Malay ethnicity, 41.3% were in the 19-44 year old age group and 15.2% were from Sabah, with the East region having the highest registered number of vWD cases. In Malaysia, most patients are predominately affected by vWD type 1 (77.2%). Factor 8, von Willebrand factor: Antigen and vWF: Collagen-Binding was the strongest determinants in the laboratory profiles of vWD.

CONCLUSION: This report has been done with great interest to provide an immense contribution from Malaysia, by revealing the statistical counts on vWD from 2011-2013.
 

..................

Citation: Periayah MH, Halim AS, Mat Saad AZ, Yaacob NS, Abdul Karim FA. Report on von Willebrand Disease in Malaysia. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2016.030
Key words: von Willebrand Disease; Malaysian report; Sociodemographic details; Laboratory profiles; Year 2011-2013.
*Correspondence: Ahmad Sukari Halim, Reconstructive Sciences Unit, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia. (Tel) +60 09 7676000; (Fax) +60 09 7656434; Email: ashalim@usm.my
Received: 09-Jan-2016; Revised: 23-Jan-2016; Accepted: 24-Jan-2016; Online first: 29-Feb-2016
Copyright: © 2016 Mercy Halleluyah Periayah, Ahmad Sukari Halim, Arman Zaharil Mat Saad, Nik Soriani Yaacob, Faraizah Abdul Karim. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Competing Interests: The authors have declared that no competing interests exist.
 

 

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