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ID Design 2012/DOOEL Skopje

Open Access Macedonian Journal of Medical Sciences.

http://dx.doi.org/10.3889/oamjms.2016.013
eISSN: 1857-9655

Case Report

 

 

Vesicoureteral Reflux Detected with 99mTc-DTPA Renal Scintigraphy during Evaluation of Renal Function


 

Nevena Manevska1*, Sinisa Stojanoski1, Venjamin Majstorov1, Daniela Pop-Gjorcheva1, Nikolina Zdraveska2, Dafina Kuzmanovska2

1Institute of Patophysiology and Nuclear Medicine, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; 2University Children's Hospital, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia

 

Abstract

 

 

BACKGROUND: Radionuclide techniques, as direct radionuclide cystography and 99mTc-DMSA scintigraphy, have been used in evaluation of vesicoureteral reflux (VUR) and reflux nephropathy (RN) in children. Dynamic 99mTc-DTPA scintigraphy is reserved for evaluation of differential renal function and obstruction in children, where hydronephrosis is detected by ultrasonography (US) pre- or postnatally.

CASE REPORT: Six year old boy was prenatally diagnosed with bilateral hydronephrosis. Postnatal, severe bilateral VUR was detected by voiding urethrocytography. US and 99mTc-DTPA scintigraphy performed in the first month of life showed small left kidney that participated with 2% in the global renal function. Bilateral cutaneous ureterostomy has been performed in order to obtain good renal drainage and promote optimal renal growth. Twelve months later, classic antireflux procedure was done. Control 99mTc-DTPA scintigraphy, 5 ys after antireflux surgery, revealed persisting radioactivity during the diuretic phase, in the left kidney that indicated antireflux procedure failure with VUR reappearance.

CONCLUSION: 99mTc-DTPA scintigraphy is the first method of choice for long-term monitoring of individual kidney function in children with VUR and other congenital urinary tract anomalies. Additionally, it can be used as indirect radionuclide cystography when rising of radioactivity in the kidney region, during the diuretic phase can indicate presence of VUR.

..................

Citation: Manevska N, Stojanoski S, Majstorov V, Pop-Gjorcheva D, Zdraveska N, Kuzmanovska D. Vesicoureteral Reflux Detected with 99mTc-DTPA Renal Scintigraphy during Evaluation of Renal Function. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2016.012
Key words: VUR; renal function; 99mTc-DTPA scintigraphy; 99mTc-DMSA scintigraphy; hydronephrosis.
*Correspondence: Dr. Nevena Manevska. Institute of Patophysiology and Nuclear Medicine, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia. E-mail: nenaribi@gmail.com
Received: 31-Oct-2015; Revised: 18-Dec-2015; Accepted: 19-Dec-2015; Online first: 31-Dec-2015
Copyright: © 2016 Nevena Manevska, Sinisa Stojanoski, Venjamin Majstorov, Daniela Pop-Gjorcheva, Nikolina Zdraveska, Dafina Kuzmanovska. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Competing Interests: The authors have declared that no competing interests exist.
 

 

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- Manevska N
- Stojanoski S
- Majstorov V
- Pop-Gjorcheva D
- Zdraveska N
- Kuzmanovska D


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- Manevska N
- Stojanoski S
- Majstorov V
- Pop-Gjorcheva D
- Zdraveska N
- Kuzmanovska D

 

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Publisher: ID Design 2012/DOOEL Skopje, Republic of Macedonia.

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