[International] [Peer Reviewed] 

About OAMJMS

Our policies

OAMJMS Online

For contributors

Services

Why publish in OAMJMS?
Editors
Boards
Publication fee
Indexing
Membership
Evaluation

Editorial & publishing policies
Competing interests policy 
Open access
Open access license

Reviewer guidelines
CrossCheck Plagiarism Screening
CrossMark Policy Page

Online first
Current issue
Journal archive

Online first fact sheet
Free Registration
Contact
Webmail

Guidelines  [pdf]
Online submission MC
Online submission OJS
Help for authors
Cover letter
Reviewers of OAMJMS

Reviewer Summary

Transliteration
Subscriptions

Sponsors
Reprints and permissions
Resources
ICMJE Disclosure Form

 

ID Design 2012/DOOEL Skopje

Open Access Macedonian Journal of Medical Sciences.

http://dx.doi.org/10.3889/oamjms.2015.131
eISSN: 1857-9655

Clinical Science

 

 

Cardiovascular Autonomic Neuropathy and Early Atherosclerosis in Adolescent Type 1 Diabetic Patient


 

Soha M. Abd El Dayem1*, Ahmed A. Battah2, Abo El Magd El Bohy3

1Pediatrics Department, National Research Centre, Cairo, Egypt; 2Critical Care Department, Cairo University, Cairo, Egypt; 3Radiology Department, Cairo University, Cairo, Egypt

 

Abstract

 

 

 

AIM: To evaluate cardiovascular autonomic neuropathy (CAN) in type 1 Diabetics and to detect its relation to coronary artery calcification.

PATIENTS AND METHODS: It is a cross sectional study included 62 diabetics and 30 controls. Clinical, laboratory assessment and 24 Hr holter were done for all patients and controls and coronary artery calcium (CAC) scoring by multisclice CT was done for all patients only. T-test, Mann Whitney U test, and stepwise multiple regression were used for statistical analyses.

RESULTS: CAC score was positive in 8.1 % of patients. Heart rate variability (HRV) was significantly lower in diabetics. All parameters of HRV were insignificantly lower in diabetics with positive CAC score. Patients with microalbuminuria had a significantly lower HRV. HRV had a significant correlation with age of patients, duration of disease, HbA1, and Qtc in diabetics.

CONCLUSION: Percentage of arrhythmia and early atherosclerosis is high in adolescent type 1 diabetic patients. CAN is associated with early atherosclerosis. Cardiac autonomic neuropathy is associated with older age, longer duration, and poor glycemic control and microalbuminuria.

..................

Citation: Abd El Dayem SM, Battah AA, El Bohy AEM. Cardiovascular Autonomic Neuropathy and Early Atherosclerosis in Adolescent Type 1 Diabetic Patient. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2015.131
Key words: Cardiovascular autonomic neuropathy; coronary calcification; type 1 diabetic patient.
*Correspondence: Soha M. Abd El Dayem. Professor of Pediatrics, Consultant of diabetes and Endocrinology, Pediatrics Department, Medical Research Division, National Research Centre, Cairo, Egypt. Telephone: +2 01006716852. E-mail: S_eldayem@Yahoo.com
Received: 20-Jul-2015; Revised: 10-Sep-2015; Accepted: 11-Sep-2015; Online first: 13-Dec-2015
Copyright: © 2015 Soha M. Abd El Dayem, Ahmed A. Battah, Abo El Magd El Bohy.    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Competing Interests: The authors have declared that no competing interests exist.
 

 

< Previous | Next Article >

Table of contents

 

This Article (free)

Full text (pdf)

Full text OnlineFirst (pdf)


Google Scholar

- Abd El Dayem SM
- Battah AA
- El Bohy AEM


PubMed

- Abd El Dayem SM
- Battah AA
- El Bohy AEM

 

Altmetric
 

 


Publisher: ID Design 2012/DOOEL Skopje, Republic of Macedonia.

This journal is a member of and subscribes to the principles of the Committee on Publication Ethics.

OAMJMS is an international peer-reviewed, Open Access journal published four times per year. OAMJMS Online (eISSN 1857-9655) offers free access to all articles.


Creative Commons Attribution LicenseAll site content, except where otherwise noted, is licensed under a Creative Commons Attribution License.