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ID Design 2012/DOOEL Skopje
Open Access Macedonian Journal of Medical Sciences.
http://dx.doi.org/10.3889/oamjms.2015.114
eISSN: 1857-9655
Case Report
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Antiphospholipid Syndrome - A
Case Report of Pulmonary Thromboembolism, Followed with Acute Myocardial
Infarction in Patient with Systemic Sclerosis
Marija Vavlukis*, Irina Kotlar, Emilija
Chaparoska, Bekim Pocesta, Hristo Pejkov, Marjan Boshev, Sasko Kedev
University Clinic of Cardiology, Faculty of Medicine, Ss Cyril and Methodius
University of Skopje, Skopje, Republic of Macedonia
AIM: We are presenting an uncommon case of pulmonary embolism,
followed with an acute myocardial infarction, in a patient with progressive
systemic sclerosis.
CASE PRESENTATION: A female 40 years of age was admitted with signs
of pulmonary embolism, confirmed with CT scan, which also reviled a thrombus
in the right ventricle. The patient had medical history of systemic
sclerosis since the age of 16 years. She suffered an ischemic stroke 6 years
ago, but she was not taking any anticoagulant or antithrombotic medications
ever since. She received a treatment with thrombolytic therapy, and
subsequent UFH, but, on the sec-ond day after receiving fibrinolysis, she
felt chest pain accompanied with ECG changes consistent for ST-segment
elevation myocardial infarction (STEMI). Urgent coronary angiography was
undertaken, which reviled cloths causing total occlusion in 4 blood ves-sels,
followed with thromboaspiration, but without successful reperfusion. Several
hours later the patient developed rapid deterioration with letal ending.
During the very short hospital course, blood sampling reviled presence of
antiphos-pholipid antibodies.
CONCLUSION: The acquired antiphospholipid syndrome is common
condition in patients with systemic autoimmune diseases, but relatively rare
in patients with systemic sclerosis. Never the less, we have to be aware of
it when treating the patients with systemic sclerosis.
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Citation: Vavlukis M, Kotlar I, Chaparoska E,
Pocesta B, Pejkov H, Boshev M, Kedev S. Antiphospholipid Syndrome - A Case
Report of Pulmonary Thromboembolism, Followed with Acute Myocardial
Infarction in Patient with Systemic Sclerosis. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2015.114
Key words: systemic sclerosis; antiphospholipid syndrome;
protrombotic state; pulmonary thromboembolism; myocardial infarction.
*Correspondence: Dr. Marija Vavlukis. UC of Cardiology, ICCU, Mother
Theresa 17, Skopje 1000, Republic of Macedonia. Phone: 003892 3113116. Fax:
003892 3164134. E-Mail: marija.vavlukis@gmail.com
Received: 25-Oct-2015; Revised: 02-Oct-2015; Accepted: 03-Nov-2015; Online
first: 08-Nov-2015
Copyright: © 2015 Marija Vavlukis, Irina Kotlar, Emilija Chaparoska,
Bekim Pocesta, Hristo Pejkov, Marjan Boshev, Sasko Kedev.
This is an open access article distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use, distribution,
and reproduction in any medium, provided the original author and source are
credited.
Competing Interests: The authors have declared that no competing
interests exist.
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Vavlukis M
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Chaparoska E
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Pejkov H
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