ID Design 2012/DOOEL Skopje
Open Access Macedonian Journal of Medical Sciences.
http://dx.doi.org/10.3889/oamjms.2015.111
eISSN: 1857-9655
Review Article
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Hepatocellular Carcinoma: Risk
Factors, Diagnosis and Treatment
Dafina Janevska1, Viktorija Chaloska-Ivanova1,
Vlado Janevski2
1University Clinic of Gastroenterohepatology, Faculty of
Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of
Macedonia; 2University Clinic of Abdominal Surgery, Faculty of
Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of
Macedonia
Hepatocellular carcinoma (HCC) is the most often primary cancer of the liver
and is one if the leading cause of cancer-related death worldwide. The
incidence of HCC has geographic distribution with the highest levels in
countries with developing economies. Patients with hepatocellular carcinoma
have poor prognosis despite the achievements in surgery techniques and other
therapeutic procedures and it is a reason why continuous attention should be
paid to this issue.
This article provides an overview of this disease based on an extensive
review of relevant literature. The article summarizes the current risk
factors, diagnosis, staging and the management of HCC.
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Citation: Janevska D, Chaloska-Ivanova V, Janevski
V. Hepatocellular Carcinoma: Risk Factors, Diagnosis and Treatment. OA Maced
J Med Sci. http://dx.doi.org/10.3889/oamjms.2015.111
Key words: hepatocellular carcinoma; risk factors; diagnosis;
management; review article.
*Correspondence: Dr. Dafina Janevska. University Clinic of
Gastroenterohepatology, Faculty of Medicine, Ss Cyril and Methodius
University of Skopje, Skopje, Republic of Macedonia E-mail: dafina.janevska@gmail.com
Received: 20-Oct-2015; Revised: 23-Oct-2015; Accepted: 27-Oct-2015; Online
first: 29-Oct-2015
Copyright: © 2015 Dafina Janevska, Viktorija Chaloska-Ivanova, Vlado
Janevski.
This is an open access article distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use, distribution,
and reproduction in any medium, provided the original author and source are
credited.
Competing Interests: The authors have declared that no competing
interests exist.
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