Open Access Macedonian Journal of Medical Sciences.
Gender Associated High Body Mass
Index in Allergic Diseases
Violeta Lokaj-Berisha1*, Besa Gacaferri-Lumezi1,
Ganimete Minci–Bejtullahu1, Hatixhe Latifi-Pupovci1,
Natyra Karahoda–Gjurgjeala1, Naser Berisha2, Teuta
1Department of Physiology & Immunology, Faculty of Medicine,
University of Prishtina, Prishtina, Republic of Kosovo; 2Department
of Obstetrics and Gynecology, University Clinical Center, Prishtina,
Republic of Kosovo; 3Faculty of Medicine, University of Prishtina,
Prishtina, Republic of Kosovo
BACKGROUND: The increasing prevalence of allergic diseases and atopy
is affected by sex, age and lifestyle factors. Obesity and excess weight are
reported to be potential risk factors for atopy and specifically for asthma
symptoms in children and adults.
OBJECTIVE: To assess the relation between body mass index (BMI) and
allergic diseases in patients of both genders, as well as association of BMI
with atopy in healthy subjects.
METHODS: BMI (kg/m2), skin-prick test and total serum immunoglobulin
E levels were assessed in 139 subjects: 109 were patients with allergic
diseases (M to F ratio was 51:58) and 30 were healthy controls (M to F ratio
RESULTS: The study population was grouped into asthma, asthmarhinitis,
rhinitis, Urticaria oreczema and controls by BMI and sex. Females with the
highest BMI were in asthma and urticaria/eczema group. Males with the
highest BMI were in asthmarhinitis and urticariaeczema group. High BMI was
associated with atopy in both genders of healthy controls. High levels of
total IgE were in male allergic patients.
CONCLUSION: High BMI was associated with asthma in females, urticaria/eczema
in both genders and atopy in both genders of healthy controls. Higher levels
of total IgE were concluded in male patients.
Citation: Lokaj-Berisha V, Gacaferri-Lumezi B,
Minci–Bejtullahu G, Latifi-Pupovci H, Karahoda–Gjurgjeala N, Berisha N,
Morina T. Gender Associated High Body Mass Index in Allergic Diseases. OA
Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2015.008.
Key words: allergy; atopy; body mass index; gender; total IgE;
Republic of Kosovo.
*Correspondence: Violeta Lokaj-Berisha, MD, MSc, PhD candidate.
Allergy and Clinical Immunolgy, Department of Physiology & Immunology,
Faculty of Medicine, University of Prishtina, Republic of Kosovo. Address:
24 Maji, no.31, Arbėri, 10000 Prishtina. Phone: +37744 185 222. E-mail:
Received: 14-Nov-2014; Revised: 18-Dec-2014; Accepted: 19-Dec-2014; Online
Copyright: © 2014 Violeta Lokaj-Berisha, Besa Gacaferri-Lumezi,
Ganimete Minci–Bejtullahu, Hatixhe Latifi-Pupovci, Natyra Karahoda–Gjurgjeala,
Naser Berisha, Teuta Morina. This is an open access article distributed
under the terms of the Creative Commons Attribution License, which permits
unrestricted use, distribution, and reproduction in any medium, provided the
original author and source are credited.
Competing Interests: The authors have declared that no competing
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- Lokaj-Berisha V
- Gacaferri-Lumezi B
- Minci–Bejtullahu G
- Latifi-Pupovci H
- Karahoda–Gjurgjeala N
- Berisha N
- Morina T