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Open Access Macedonian Journal of Medical Sciences.


Clinical Science



Association of Serum 25-Hydroxyvitamin D with Life Style and Dietary Factors in Egyptian Prepubescent Children


Moanes M. Abu Shady1, Mai M. Youssef1, Manal A. Shehata1, Ebtissam M. Salah El-Din1*, Heba A. ElMalt2

1Child Health Department, National Research Centre, Cairo, Egypt; 2Medical Biochemistry Department, Medical Division, National Research Centre, Cairo, Egypt





BACKGROUND: There had been a growing evidence of high prevalence of vitamin D deficiency especially among children which may increase the risk of many chronic diseases in adulthood.

AIM: Assessment of different lifestyles and dietary behaviour influencing the level of serum 25-OHD in a group of Egyptian prepubescent children.

SUBJECTS AND METHODS: Two hundred boys and girls aged from 9 to 11 years were recruited from two primary public schools situated in Giza governorate in Egypt. A questionnaire was developed to obtain relevant information related to age, dietary habits, and physical activity. Thorough clinical examination and measurement of weight and height were performed. Body mass index was calculated. Serum samples were assayed for 25-hydroxy vitamin D (25-OHD).

RESULTS: Low serum 25-OHD (< 20 ng/ml) was found in 11.5% of the whole sample. Mean serum 25-OHD was significantly lower in obese subjects and in those with low physical activity (p < 0.05). Multiple stepwise linear regression analysis showed that BMI and physical activity were the main predictors of serum 25-OHD (P < 0.05).

CONCLUSIONS: Lifestyle factors in terms of physical activity and BMI may contribute significantly to the optimal vitamin D status of apparently healthy children.


Citation: Abu Shady MM, Youssef MM, Shehata MA, Salah El-Din EM, ElMalt HA. Association of Serum 25-Hydroxyvitamin D with Life Style and Dietary Factors in Egyptian Prepubescent Children. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2015.006.
Key words: 25-hydroxyvitamin D; lifestyle; physical activity; BMI; children.
*Correspondence: Prof. Ebtissam Mohamed Salah El-din. National Research Center of Egypt, Child Health, ElBuhose street, Dokki, Giza, Cairo 12622, Egypt. E-Mail: ebtissam2006@yahoo.com
Received: 07-Nov-2014; Revised: 16-Dec-2014; Accepted: 17-Dec-2014; Online first: 01-Jan-2015
Copyright: 2014 Moanes M. Abu Shady, Mai M. Youssef, Manal A. Shehata, Ebtissam M. Salah El-Din, Heba A. ElMalt. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Competing Interests: The authors have declared that no competing interests exist.


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- Abu Shady MM
- Youssef MM
- Shehata MA
- Salah El-Din EM
- ElMalt HA


- Abu Shady MM
- Youssef MM
- Shehata MA
- Salah El-Din EM
- ElMalt HA




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